Baltimore, United States - February 13, 2025 A new study from Johns Hopkins University suggests that jumping exercises may help astronauts prevent cartilage damage during long space missions to the Moon and Mars, with promising results seen in mice. The groundbreaking research, published in the journal npj Microgravity, shows that jumping workouts could counteract the effects of low gravity, which cause cartilage degradation in astronauts during extended space flights. In the study, mice who performed jumping exercises over nine weeks displayed healthier, thicker cartilage compared to those with limited movement. "Cartilage damage is a major concern for astronauts as they prepare for missions to Mars," said Marco Chiaberge, an astrophysicist at Johns Hopkins University. "Our findings show that jumping can improve cartilage health, potentially offering a preventive measure for astronauts facing long periods of low gravity." Previous studies have shown that low gravity accelerates cartilage breakdown, and space radiation can make the problem worse. However, the new study found that jumping exercises could reverse some of the damage, improving both cartilage and bone strength in mice. Mice that performed jumping exercises had 26% thicker cartilage compared to those that remained inactive. While more research is needed to determine whether humans would experience the same benefits, the findings have great potential for space agencies looking for effective solutions to protect astronauts’ joints during extended space missions. With future research, jump-based training could become an essential part of astronauts’ pre-flight preparations. This study highlights how even simple exercises, like jumping, can help ensure astronauts maintain optimal health as they face the challenges of long-duration space exploration.