Louisville, United States - November 04, 2025 At least seven people were killed when a UPS cargo plane crashed while taking off from an airport in Louisville, Kentucky on Tuesday evening, the state&'s governor said. Andy Beshear said the plane&'s three crew members were likely to be among the dead after the freight plane exploded as it departed Louisville Muhammad Ali International Airport at around 17:15 local time. It is unclear whether the death toll includes the three crew members who were onboard the plane. At least 11 other people were injured when the plane crashed, sending thick plumes of black smoke into the sky. SHOTLIST Video showing smoke coming from the scene of the crash. [Credit: X/StableGeniustm]