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Woman has miracle 'Mounjaro baby' at 41 - "I didn't need IVF anymore"

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A 42-year-old Kentucky woman became pregnant with a miracle Mounjaro baby after years of battling infertility.

In July 2022, at 39, Rachael Knight Gullette, a content creator and interior designer from Lexington, Kentucky, started taking Mounjaro, a GLP-1 medication in the same class as Ozempic.

Her goal went beyond weight loss. She hoped to treat the underlying health issues that had kept her from becoming pregnant, including a hormonal disorder called polycystic ovary syndrome (PCOS).

She lost 172 pounds and saw her reproductive health improve dramatically - conceiving naturally without fertility treatments.

Now a mom to a seven-month-old baby boy, she's advocating for more awareness about how these medications can impact fertility.

Last week women using weight-loss jabs were warned by the UK's medicines regulator that they must use effective contraception.

The Medicines and Healthcare products Regulatory Agency (MHRA) warned weight-loss jabs may make the contraceptive pill less likely to work.

Reports also say for many, it can also rebalance hormonal levels, creating a more favorable environment for conception.

"I've dealt with PCOS and insulin resistance and obesity since I was eight years old. So it's been a lifelong chronic disease that I've kind of battled," Gullette explained. "

PCOS often causes irregular periods, excessive androgen levels, and the presence of small cysts on the ovaries.

"I took the medication intending to try to help my fertility because I was 39," she said. "And I knew it was kind of now or never for me to have a family."

The results were remarkable. Gullette lost 172 pounds over approximately 18 to 19 months, going from 315 pounds to 143 pounds.

But the weight loss was just one aspect of how the medication transformed her health.

"At first, I just thought it was going to help me lose weight, but ultimately, it changed the way my body and my brain worked," she said. "

"It shut off all the food noise, it helps with reward center regulation, and that's what really helped me along with helping my insulin resistance."

What surprised Gullette was how quickly the medication affected her reproductive health, even before significant weight loss occurred.

"My cycle went from 90 days to 30 days in the first two months on the medication. So way before I lost a large amount of weight," she noted. "

"Previously in my life, I've lost large amounts of weight too, and never got pregnant, never saw a difference in my cycle."

Just one month after reaching her maintenance weight, Gullette missed her cycle and discovered she was pregnant at age 41 —

without the fertility treatments she had assumed would be necessary.

"Without even really trying, we ended up pregnant," she shared. "

"I was completely shocked. We still anticipated that at 41 years old, I would have to go through fertility treatment in addition to losing weight and taking this medication."

Today, Gullette and her husband Brad, 44, a retail manager also in Lexington, are parents to seven-month-old Everett, a healthy baby boy they had nearly given up hope of ever having.

Under her TikTok username, @mylittlelovenest, Gullette has documented her journey on the platform, amassing over 80,000 followers along the way.

While Gullette's pregnancy was planned, she notes that many women taking GLP-1 medications are experiencing unexpected pregnancies, something she attributes to a lack of information from healthcare providers.

"The funny thing is, the reason there are a lot of 'Ozempic babies' is because doctors aren't really telling their patients that the medication will make them more fertile," she explained."

"And they're also not telling them that their hormonal birth control is going to be less effective."

For those considering GLP-1 medications who might want to become pregnant, Gullette notes there are medical recommendations to follow:

"The overall recommendation for this medication is to go off of it for two months before you try to conceive."

Looking toward the future, Gullette believes these medications will eventually become standard treatments for conditions like hers.

"I think eventually they will be first-line treatment for a lot of people with PCOS and infertility," she said."

"I am forever grateful for the opportunity to be on this medication."

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