This is the amusing moment a woman's face turned bright red during a 'guess the drink' game with her friend.

Footage shows Mrs Liu pouring Cola into her friend's mouth with her eyes closed, followed by another carbonated drink, which the woman successfully named in Jiangsu, China.

Moments later, the prankster friend offered a sip of beer, prompting an immediate skin reaction while the woman still had her eyes closed, trying to identify the drink on September 9.

When she finally opened her eyes, she realised it was alcohol, her eyes widening in shock as she started cursing Mrs Liu.

The dramatic flush is a phenomenon known as Asian flush, caused by a genetic variant that slows the breakdown of acetaldehyde, a toxic byproduct of alcohol, leading to facial redness and other symptoms.