Dramatic footage shows Soo Paulo plane crash fireball and smoke billowing on the street.

Police reported that two individuals on board the aircraft died after it collided with a bus on Marques de Sao Vicente Avenue in Brazil on February 7.

Two residents - one aboard the public bus and a passing motorist - were rushed to a nearby hospital after sustaining injuries from the incident.

A large plume of thick black smoke emerging from the burning plane can be seen engulfing the highway, with travellers running to safety.

Emergency responders rushed to the scene and assisted passengers aboard the public vehicle.

The cause of the crash is under investigation as authorities work to determine what led to the tragic accident.